The JHDM1a/FBXL11 Antibody (Center) from MyBioSource.com is a Rabbit Polyclonal antibody to FBXL11, JHDM1A, and KDM2A. This antibody recognizes Human antigen. The JHDM1a/FBXL11 Antibody (Center) has been validated for the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
JHDM1a/FBXL11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box),which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least 6 highly degenerated leucine-rich repeats